三酮类除草剂环磺草酮的合成工艺技术领域[0001] 本发明属于农药原药

三酮类除草剂环磺草酮的合成工艺
技术领域

[0001] 本发明属于农药原药的制备领域，具体涉及一种三酮类除草剂环磺草酮的合成工 〇

背景技术

[0002] 除草剂环磺草酮（1^11113〇廿丨〇1^)，化学名称 ：2-(2-氯4-甲磺酰基-3-[(2,2,2-三 氟乙氧基）甲基]苯甲酰基）环己烷-1，3-二酮。由拜耳公司2007年研制的三酮类玉米 田除草剂，其活性高于目前市场上的硝环磺酮和甲基磺草酮，对作物安全。对多种杂草有很 强的杀灭作用，无残留活性，有较强的抗雨水冲刷能力，且除草谱广，能有效防除辣子草属、 旋花属、婆婆纳属、猪殃殃等杂草。

[0003] 现有技术采用的合成路线有以下缺点：（1)采用甲硫醇钠气味比较大，废水中的 硫醇难于处理，造成环境污染；（2)生产成本过高；（3)采用N-溴琥珀酸亚胺作溴化剂，该 溴化剂昂贵。

发明内容

[0004] 本发明所要解决的技术问题在于针对上述现有技术而提出一种三酮类除草剂环 磺草酮的合成工艺，通过改进其工艺路线，缩短了工艺反应时间，革除了气味大的甲硫醇钠 和剧毒氰基丙酮，提高了收率，三废少，实现了清洁环保生产。

Results (English) 1:

Sulcotrione trione herbicides ring synthesisTechnical field[0001] this invention belongs to a field of pesticide preparation, relates to three ketone synthesis sulcotrione herbicide ring 0Background art[0002] herbicides ring sulcotrione (1 ^ 11,113,020--0 1^), chemical name: 2-(2-chloro-4-methyl-sulfonyl -3-[(2,2,2-Ethoxy III) methyl] benzoyl) -1,3-two ketone of cyclohexane. Developed by the Bayer company in 2007 the three ketones corn herbicide, its activity is higher than the current market ring sulfonation nitrate ketone and methyl sulcotrione, safe to crops. Has a strong effect on many species, with no residual activity, have a strong ability to resist rain and broad-spectrum, effectively on controlling weeds in Capsicum genus, Convolvulus, the genus Veronica, cleavers and other weeds.[0003] existing technology used synthetic routes have the following disadvantages: (1) using sodium methyl mercaptan odor is relatively large, mercaptan is more difficult to deal with in the wastewater, environmental pollution and (2) production costs are too high, (3) using n-bromo-succinimide as bromide, and expensive the brominating agent.Contents of invention[0004] technical problem solved by the invention lies in response to these existing technologies is presented-trione sulcotrione herbicides ring synthesis, through the improvement of its process, shortens the reaction time, get rid of the smell of sodium methyl mercaptide and highly toxic cyano-acetone, increased yield, less waste, realize clean production.

Results (English) 2:

Three herbicides sulcotrione ring synthesis process
Technical Field

[0001] The present invention belongs to the field of preparation of pesticide, particularly to a three-ring herbicides sulcotrione synthetic workers billion

BACKGROUND

[0002] The herbicidal agent cyclic sulcotrione (^ 1 ^ 〇1 11113〇 Twenty Shu), chemical name: 2- (2-chloro-4-methanesulfonyl-3 - [(2,2,2-trifluoroethoxy) methyl ] benzoyl) cyclohexane-1,3-dione. Developed by Bayer in 2007 three ketones cornfield herbicides, and its activity is higher than the current one and sulfur nitrate ring mesotrione on the market for crop safety. A variety of weeds has a strong role in the killing, no residual activity, there is a strong resistance to rain erosion capacity, and weed control spectrum, can effectively control Spicy grass genus Convolvulus, Veronica, cleavers, etc. weeds.

[0003] The synthetic routes used in the prior art has the following disadvantages: (1) using sodium thiomethoxide odor is relatively large, difficult to handle wastewater thiol, causing environmental pollution; (2) high production costs; (3) N- bromo-succinimide as the brominating agent, the agent bromide expensive.

SUMMARY OF THE INVENTION

[0004] The technical problem to be solved is that of the prior art proposed for the synthesis of a three-ring herbicides sulcotrione by improving its process route, shortening the process reaction time, get rid of the smell a large and highly toxic methyl mercaptan sodium cyano acetone, improved yield, less waste, to achieve a clean and green production.

Results (English) 3:

Synthesis of three ketone ring herbicide sulcotrionetechnical fieldThe invention belongs to the field of preparation of [0001] pesticide, in particular to a three ring herbicide sulcotrione ketone synthesis technology 2010Background technology[0002] ring herbicide sulcotrione (1^11113, 20, 0 1^), 2- (chemical name: 2- 4- -3-[(methylsulfonyl chloride three 2,2,2- fluoride ethoxy) methyl] benzoyl) cyclohexane -1, 3- two. By three ketones Maize Herbicide Bayer developed in 2007, its activity is higher than that currently on the market - ring sulfonyl ketones and mesotrione, crop safety. Have a strong role in the killing of many weeds, no residual activity, anti rain erosion ability, and wide herbicidal spectrum, can effectively control the spicy Mimosa, Convolvulus, Veronica, catchweed weeds.The synthetic route has the following disadvantages using [0003] existing technology: (1) using sodium methyl mercaptide relatively large odor, mercaptan in wastewater is difficult to be treated, causing environmental pollution; (2) the production cost is too high; (3) using N- bromo succinimide as brominating agent, the brominating agent expensive.summary of the inventionThe invention solves the technical problem of the [0004] that in the light of the existing technology and proposed a synthesis technology of three ketones herbicide sulcotrione ring, by improving the process, shorten the reaction time, get rid of the smell of the cyano and highly toxic sodium methyl mercaptide acetone, high yield, less waste, to achieve cleaner production.