三酮类除草剂环磺草酮的合成工艺本发明涉及一种三酮类除草剂环磺草酮的合成

三酮类除草剂环磺草酮的合成工艺

本发明涉及一种三酮类除草剂环磺草酮的合成工艺，包括有以下步骤：1)2-氯-6-甲磺酰基甲苯的合成；2)2-氯-3-乙酰基-6-甲磺酰基甲苯的合成；3)2-氯-3-甲基-4-甲磺酰基苯甲酸的合成；4)2-氯-3-甲基-4-甲磺酰基苯甲酸甲酯的合成；5)2-氯-3-溴甲基-4-甲磺酰基苯甲酸甲酯的合成；6)2-氯-3-(2,2,2-三氟乙氧基)甲基-4-甲磺酰基苯甲酸的合成；7)2-氯-3-(2,2,2-三氟乙氧基)甲基-4-甲磺酰基苯甲酸3-氧代-1-环己烯酯的合成；8)环磺草酮的合成。本发明的有益效果在于：缩短了反应步骤和时间，提高了中间体的收率；反应条件更温和，更安全；成本降低。

Results (English) 1:

Sulcotrione trione herbicides ring synthesisThis invention involved a three ketone class herbicide ring sulfonic grass ketone of synthesis process, including has following steps: 1) 2-chlorine -6-methyl sulfonic acyl toluene of synthesis; 2) 2-chlorine -3-acetyl base -6-methyl sulfonic acyl toluene of synthesis; 3) 2-chlorine -3-methyl -4-methyl sulfonic acyl benzoic acid of synthesis; 4) 2-chlorine -3-methyl -4-methyl sulfonic acyl benzoic acid methyl ester of synthesis; 5) 2-chlorine -3-bromide methyl -4-methyl sulfonic acyl benzoic acid methyl ester of synthesis; 6) 2-chlorine -3-(2,2,2- III fluorine Ethoxy) methyl-methyl sulfonyl acid synthesis; 7) 2-chloro (2,2,2-Ethoxy III) methyl-methyl sulfonyl acid 3-oxo synthesis of cyclohexene; 8) synthesis of cyclic sulcotrione. The beneficial effect of the invention are: steps and shortens the reaction time, improved the yield of intermediate reaction conditions are mild, more secure; cost is reduced.

Results (English) 2:

Three herbicides sulcotrione ring synthetic process

of the present invention relates to a three-ring herbicides sulcotrione synthetic process comprising the following steps: 1 Synthesis methylsulfonyl toluene) of 2-chloro-6; 2) synthesis of 2-chloro-3-acetyl-6-mesyl toluene; 3) -3-methyl-2-chloro-4-methanesulfonyl-benzoic acid; 4) -3-chloro-2- synthesis of 4-methanesulfonyloxy-yl benzoate; and 5) synthesis of 2-chloro-3-bromo-4-methanesulfonyl-methyl-benzoate; and 6) of 2-chloro-3- (2,2 , synthesis-trifluoroethoxy) methyl-4-methanesulfonyl-benzoic acid; 7) of 2-chloro-3- (2,2,2-trifluoroethoxy) methyl-4-sulfonic synthesis of benzoic acid 3-oxo-1-cyclohexen-acetate; 8) synthesis of cyclic sulcotrione. The beneficial effect of the present invention is that: the reaction step and shortening the time and improve the yield of intermediates; more mild reaction conditions, more safety; reduce costs.

Results (English) 3:

Synthesis of three ketone ring herbicide sulcotrioneThe invention relates to a synthesis process of three ketone ring herbicide sulcotrione, comprising the following steps: 1) the synthesis of 2- chloro -6- methyl sulfonyl toluene; 2) synthesis of 2- chloro -3- acetyl -6- methyl sulfonyl toluene; 3) synthesis of 2- chloro -3- methyl -4- methyl sulfonyl benzoic acid; 4 the synthesis of 2- methyl -4- chloride) -3- methyl sulfonyl benzoic acid methyl ester; 5) synthesis of 2- chloro -3- methyl bromide -4- methyl sulfonyl methyl benzoate; 6) 2- chloro -3- (2,2,2- three fluorine ethoxy) synthesis of methyl -4- methyl sulfonyl benzoic acid; 7 2- -3- (2,2,2-) three fluorine chlorine ethoxy) synthesis of methyl -4- methyl sulfonyl benzoic acid 3- oxo -1- cyclohexene ester; 8) synthesis of cyclic sulcotrione. The invention has the advantages that: the reaction steps and time are shortened, the yield of the intermediate is improved, the reaction conditions are more moderate, and the cost is lower.